Needle-less® Serum
Needle-less® Serum
Firming Plumping Serum
★★★★★4377Read ReviewsVisibly smoother and deeply hydrated skin—no injections needed. This award-winning anti-aging serum was developed with a multi-active system that helps bind moisture, visibly smooth fine lines, and support barrier reinforcement through targeted hydration dynamics.
- Visibly plumps and smooths fine lines
- Deeply hydrates and reinforces the skin barrier
- Targets dullness and redness
Couldn't load pickup availability

Full Description
As skin matures, it can begin to look less firm and smooth, with more visible lines and uneven texture. Daily exposure to environmental stressors can also weaken the skin’s protective barrier, making it more prone to dryness and visible redness.
Needle-less® Serum was formulated to address these visible signs of aging and support the skin’s barrier to prevent moisture loss. This dual-action formula helps improve the appearance of firmness, visibly smooth texture, and deliver lasting hydration.
Key Facts
- Absorbs quickly and layers well under other treatments or moisturizer
- Fragrance-free and suitable for all skin types
- Can be used day and/or night
Skincare Technology
CERAPEP® TECHNOLOGY
A revolutionary blend of restorative peptides & ceramides
NIACINAMIDE
Helps even skin tone
COPPER PEPTIDE COMPLEX
Enhances skin renewal and firmness
SODIUM HYALURONATE
Penetrates deeply, attracts water and hydrates skin
Dramatic Anti-aging Results You Can See After 6 Weeks
saw healthier-looking skin
had firmer-feeling skin
said skin felt smoother
*Based on a six-week independent consumer panel.
Skin Concerns
- Redness
- Firmness
- Wrinkles
- Dryness
- Post Procedure
Skin Types
- Normal
- Dry
- Combination
- Oily
Frequently Asked Questions
Is Needle-less Serum safe for sensitive skin?
Yes, this serum is suitable for all skin types, including sensitive and oily skin. It's a perfect serum for those wanting anti-aging results without a heavy feel or irritation.
Can I use it with retinoids?
Yes, this serum pairs perfectly with retinoids in your evening routine. Apply serum first, allow to absorb fully before applying retinoid.
When will I see results?
Consistency and patience is key. You will start to notice results in a few weeks but we recommend using 2X a day for 6-8 weeks to see real results.
How should I incorporate this into my routine?
Apply to slightly damp skin as the first step in your AM & PM routine after cleansing and toning.
Can I use Needle-less Serum if I get injectables?
Absolutely! This serum will prolong results of your injectables. If you do not get injectables, this makes for a perfect non-invasive alternative option.
What are people saying about Needle-less® Serum?
Based on 4377 reviews
Vicki
5 star
This is the best product I have ever purchased. It is so good I do not need to get Botox injections as often!
Heather L.C.
Wonderful!
My skin loves this serum. It’s so hydrating and plumping. I’ve taken time off from using it to test its effectiveness and my skin loses its radiance when I don’t use it. This is one of my must have products.
The Core3™
DRMTLGY's research-driven method for smarter aging—built on 3 key actives that work in sync to renew your skin:
Brighten.
Vitamin C E + F
Shields skin from daily environmental stress and helps balance tone for a brighter, healthier-looking complexion.
Protect.
Universal Tinted Moisturizer SPF 46
A dewy, lightweight, oil-free hybrid sunscreen with sheer coverage that evens out skin while delivering broad spectrum SPF 46 protection.
Renew.
Retinol Complex 0.5%
Visibly softens the look of fine lines, refines pores and texture, and supports long-term skin renewal.
How to Layer Needle-less® Serum
Complete Your Regimen
Needle-less® Growth Factor Serum
Needle-less® Serum
Advanced Eye Cream
Pumpkin Enzyme Mask
FacialRX™ Brightening Eye Masks
TINGL® Exfoliating Pads
HPR Eye Cream
Barrier Repair Mask
Retinol Complex 0.5%
Best Selling Bundles
-
25% OFF
FacialRX™ Duo
A targeted duo made to visibly brighten, smooth and add radiance to skin.
-
25% OFF
-
25% OFF
The Needle-less® Duo
An advanced duo built to visibly firm, smooth and lift the look of skin.
-
25% OFF
The Best Sellers Bundle
Our three top-selling products, together in one easy routine.
-
25% OFF
Anti-Aging Bundle
An easy routine designed to target the common signs of aging.
-
Up to 30% OFF

