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Needle-less® Growth Factor Serum

Needle-less® Growth Factor Serum

1 fl oz

Clinically proven to visibly improve the look of aging skin, Needle-less® Growth Factor Serum features 5 bio-engineered peptides inspired by the skin’s natural renewal processes. This biotech-powered formula helps enhance the appearance of firmness, smooth texture, and reveal a more youthful-looking complexion.

  • Clinically shown to improve the look of firmness and texture in 8 weeks
  • Visibly smooths and firms the appearance of skin
  • Revitalizes the look of skin for a more youthful appearance
  • Inspired by the skin’s natural renewal signals to improve the look of elasticity
 (739 Reviews)
Regular price $69.00
Regular price $69.00 Sale price
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Before
After

Before and After 12 Weeks Of Use

When using the Needle-less® Growth Factor Serum as directed. Unedited and not retouched. Results may vary.

Discover Next-Gen Skincare, Backed by Biotech

Discover Next-Gen Skincare, Backed by Biotech

Discover Next-Gen Skincare, Backed by Biotech

90%
of participants showed visible improvement by week 12*
73%
of performance indicators showed DRMTLGY outperformed SkinMedica's $295 TNS Advanced+ Serum*
30%
greater visible improvement than SkinMedica's $295 TNS Advanced+ Serum*
*Based on a 12 week double-blind IRB-approved clinical trial of 20 participants.

4 Reasons You’ll Love Needle-less® Growth Factor Serum

001

Mimics the Skin's Natural Regenerative Signals

A blend of 5 bio-engineered growth factor peptides mimics your skin’s repair messengers, encouraging faster cell renewal without the use of human-derived ingredients.

002

Visibly Lifts & Firms

Clinically tested to deliver real results. 90% of participants noticed skin felt firmer, improved clarity & tone, and an improvement in overall appearance in just 12 weeks.*

003

Outperformed the Leading Growth Factor Serum at ¼ the price

In a 12-week IRB-approved, randomized, double-blinded, controlled clinical trial, our formula delivered 30% greater overall visible improvement, without the $295 price tag.

004

Repairs & Strengthens Skin Barrier

This serum features our CeraPep™ Technology, a proprietary blend of ceramides and peptides that restores the barrier’s essential lipids. So not only does this all-new formula lift and firm, but it’s proven to strengthen skin’s barrier after just one use.

Dr. Dayan on Needle-less® Growth Factor Serum:

“In this 12-week clinical study, participants were split into two groups—each applying a different topical treatment twice daily. Preliminary results showed visible improvements in wrinkles, texture, and firmness across both groups. One group used DRMTLGY's product, while the other used SkinMedica’s TNS Advanced+ Serum priced 4x more. However, the formula developed by DRMTLGY demonstrated notably superior results in skin texture and firmness.”

Dr. Steven H. Dayan

Dr. Dayan on Needle-less® Growth Factor Serum:

Dr. Steven H. Dayan

MD, FACS

The problem with most anti-aging serums is simple: they promise results but rarely prove they work. Many claim to smooth, firm, and lift—but where’s the evidence?

When we created Needle-less® Growth Factor Serum, we set out to do things differently. Instead of adding just another product to the lineup, we took a smarter approach—grounded in advanced technology and proven by real clinical testing.

In a 12-week, double-blind, IRB-approved clinical trial, Needle-less® Growth Factor Serum was tested head-to-head against SkinMedica’s TNS Advanced+ Serum, the industry’s best-known growth factor serum (sold at nearly 4x the price). The results spoke for themselves:

  • Investigator-assessed improvements in skin texture and firmness were significantly higher for Needle-less® at both Week 8 and Week 12
  • On the Global Aesthetic Improvement Scale (GAIS) at Week 12, Needle-less® Growth Factor Serum showed 30% greater overall improvement than the competitor
  • It outperformed the leading growth factor serum in 73% of performance indicators

 

In other words, this isn’t just another serum with empty promises. It’s clinically proven skincare technology that reframes how we approach aging—helping skin look visibly lifted and visibly renewed.

Directions

Apply 1-2 pumps to clean skin in the morning or evening. Can be used daily or as directed by a physician.

Ingredients

Ingredient Highlights: Sodium Hyaluronate, Palmitoyl Tripeptide-1, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Ceramide NP, Folic Acid, Phytosphingosine, Ceramide AP, Ceramide EOP, Chiretta (Swertia Chirata) Extract, Mushroom (Tremella Fuciformis) Sporocarp Extract

 

All Ingredients: Water/Aqua/Eau, Glycerin, Butylene Glycol, Pentylene Glycol, Maltodextrin, Coco-Caprylate/Caprate, Saccharide Isomerate, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Ceramide NP, Folic Acid, Phytosphingosine, Ceramide AP, Ceramide EOP, Triheptanoin, Chiretta (Swertia Chirata) Extract, Phenoxyethanol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C9-12 Alkane, Polyurethane-100, Ethylhexylglycerin, Sodium Hydroxide, Lecithin, Trisodium Ethylenediamine Disuccinate, Acetyl Glutamine, 1,2-Hexanediol, Mushroom (Tremella Fuciformis) Sporocarp Extract, Hydrolyzed Hyaluronic Acid, Decyl Glucoside, Bacillus/Soybean Ferment Extract, Sodium Lauroyl Lactylate, Caprylyl Glycol, Carbomer, Polysorbate 20, Cholesterol, Xanthan Gum

 

DRMTLGY is dedicated to maintaining the accuracy of the ingredient lists on this website. However, because ingredients are subject to change, we cannot guarantee that these lists are error-free. For an accurate listing of ingredients in each product, please refer to your product packaging.

Skin Concerns

  • Wrinkles
  • Firmness
  • Texture
  • Dullness

Skin Types

  • Normal
  • Oily
  • Dry
  • Combination

How to Layer Needle-less® Growth Factor Serum

Complete Your Regimen

What are people saying about Needle-less® Growth Factor Serum?

Customer Reviews
4.52
796 Verified Reviews
Reviews with media 45
5 Stars
541
4 Stars
175
3 Stars
48
2 Stars
16
1 Star
16

Based on verified customer reviews, the Needle-less® Growth Factor Serum helps reduce the appearance of fine lines and provides deep hydration. Reviewers note that their skin feels firmer and looks smoother with regular use.

This is an AI-generated summary of verified customer reviews.

Likes
Fine Lines Plumping Hydration Fast-Absorbing
Dislikes
No Trending Dislikes
Hydration
DryHydrated
Complexion
DullGlowy
Texture
RoughSmooth
Skin Comfort
SensitiveCalm
4.66 out of 5
Based on 739 reviews
Write a review
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